Challenge test for cough and pharynx discomfort expressions by a ACE inhibitor (Imidapril).

Effects of enalapril and imidapril in the capsaicin cough challenge test and spirometry parameters in healthy volunteers

Angiotensin-Converting Enzyme (ACE) Gene Insertion/Deletion Polymorphism and ACE Inhibitor-Related Cough: A Meta-Analysis

OBJECTIVE An insertion/deletion (I/D) variant in the angiotensin-converting enzyme (ACE) gene was associated with ACE inhibitor (ACEI)-related cough in previous studies. However, the results were inconsistent. Our objective was to assess the relationship between the ACE I/D polymorphism and ACEI-related cough by meta-analysis and to summarize all studies that are related to ACE I/D polymorphism...

Angiotensin converting enzyme (ACE) inhibitor-induced cough and substance P.

BACKGROUND Angiotensin converting enzyme (ACE) inhibitors cause coughing in 5-10% of patients, but the exact mechanisms of this effect are still unclear. In the airways ACE degrades substance P so the cough mechanism may be related to this peptide. METHODS Nine patients who developed a cough and five patients who did not develop a cough when taking the ACE inhibitor enalapril (2.5 or 5.0 mg/d...

Pneumonia and ACE inhibitors--and cough.

Angiotensin converting enzyme (ACE) inhibitors are widely used to treat heart failure and hypertension. They act through blocking the conversion of angiotensin I to angiotensin II; this inhibits the breakdown of bradykinin, which in turn lowers arteriole resistance and increases venous return. Many patients taking ACE inhibitors experience a persistent dry cough, which is thought to be caused b...

Whooping cough--still a challenge.

☆ Como citar este artigo: Korppi M. Whooping cough – still a challenge. ☆☆ Ver artigo de Ferronato AE et al. nas páginas 549-53. diagnosticadas como casos de coqueluche, e posteriormen-te transmitiram a bactéria B. pertussis aos neonatos das famílias. Durante as duas últimas décadas do século passa-do, muitos pais recusaram a vacinação contra pertussis, e a incidência de coqueluche mais uma vez...